Sodium lauryl sulphte(SLS) is a sodium salt of sulphuric acid mono dodecyl ester. It is mainly used as surface-active agent in detergents/or wetting agent in cosmetics, food, pharmaceuticals and different toiletry preparations.It produces adverse reactions when used in higher concentrations as in case of cosmetics (e.g. shampoos). Its severetoxic effects including irritation to the skin, eyes, mucous membranes, upper respiratory tract, and stomach. Repeated, prolonged contact can cause drying and cracking of the skin.This shows the need to determine SLS from shampoos- the most widely used cosmetics now-a-days. The determination of SLS various methods was use such as: potentiometric, Spectrophotometric using colorimerty, uv-visible spectrophotometer, Thin layer chromatography, Gas chromatography, HPLC, LC-MS, capillary zone electrophoresis. This review is about different methods for the detection of such a critical ingredient - sodium lauryl sulphate
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